Other Controls and Reagents
Medchemexpress LLC Dlin-M-C4-DMA | 1226909-66-5 | C44H81NO2 | 25 MG
DLin-M-C4-DMA (Compound MC4) is a cationic lipid designed for the efficient delivery of nucleic acids.
- Cationic lipid for delivery of nucleic acids
- Molecular formula: C44H81NO2
- Molecular weight: 656.12
- Purity: 98.0%
- Appearance: Colorless to light yellow liquid
- Soluble in DMSO (100 mg/mL)
- Can be suspended in 10% DMSO, 90% (20% SBE-β-CD in saline) at 2.5 mg/mL
- Can be dissolved in 10% DMSO, 90% corn oil at ≥ 2.5 mg/mL
Apexbio Technology LLC 1 2-Distearoyl-sn-glycero-3-PC 500mg
1 2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) is a phospholipid used in the synthesis of liposomes and lipid nanoparticle (LNP) systems for research related to mRNA vaccines or drug delivery systems
Avanti Polar Lipids PLUNGER ASSY FOR 1000UL SYRING
Plunger Assembly for 1000μL Hamilton Syringe 610032
Cayman Chemical 1 2-DIoleoyl-sn-glycerol 100mg
An analog of the PKC-activating second messengers collectively called DAG; equipotent to 1,2-dioctanoyl-sn-glycerol in induction of the acrosome reaction in human sperm
Avanti Polar Lipids 7-dehydrocholesterol | 434-16-2 | 5mg
7-dehydrocholesterol | Purity: 95% | Mol Wt: 384.644 | 434-16-2 | 5mg
Cayman Chemical 25-hydroxy Cholesterol 100mg
An oxysterol; suppresses endogenous cholesterol synthesis by binding INSIG proteins and preventing SREBPs from being transported to the Golgi; inhibits IgA class switching induced by LPS and various cytokines in B cells (IC50 = ~50 nM); inhibits replication of SARS-CoV-2 in Vero cells (EC50 = 3.675 µM) and reduces increases in viral protein production in infected Vero cells when used prior to infection; reduces viral RNA loads in the lung and trachea in a mouse model of SARS-CoV-2 infection at 100 mg/kg per day; serum levels are increased in patients with SARS-CoV-2.
Medchemexpress LLC Monophosphoryl lipid A (Glucopyranosyl lipid A) | 1246298-63-4 | 99.9% | 1 MG
Monophosphoryl lipid A (Glucopyranosyl lipid A) is a toll-like receptor 4 agonist derived from the cell wall of nonpathogenic Salmonella. It is used for research on immunization and vaccines.
- Induces NF-κB activation.
- Modulates TLR2.
- Induces IL-12 production by human dendritic cells.
- Up-regulates dendritic cell surface markers.
- Enhances T cell responses.
- Increases calcium mobilization of activated T cells.
- Activates APC and enhances the generation of both Th1- and Th2-specific immune response in mice.
Medchemexpress LLC Dspe-peg2000-pdp | 474922-24-2 | >90.0% | C140H273N4O55PS2 | 50 MG
DSPE-PEG2000-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications.
- Used in drug delivery applications.
Medchemexpress LLC DLin-KC2-DMA | 1190197-97-7 | ≥98.0% | 642.09 | 25 MG
DLin-KC2-DMA is an ionizable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). It produces significant siRNA-mediated gene silencing of GAPDH when bound to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies.
- Ionizable cationic lipid (pKa≈6).
- Virtually non-toxic to antigen presenting cells (APCs).
- Produces significant siRNA-mediated gene silencing of GAPDH when bound to lipid nanoparticles (LNP).
- Can be used in siRNA delivery studies.
- High uptake into macrophages and dendritic cells.
- Efficiently promotes release of encapsulated siRNA into the cytosol following uptake via the endocytotic pathway.
- Displays almost no toxicity in primary APCs.
- Effective in silencing target genes in APCs in vivo (5 mg/kg; i.v.; single).
Avanti Polar Lipids 16:1 (Δ9-Cis) PC, 4724-96-3, MFCD00214374, chloroform, 25mg, 10mg/mL 2.5mL
Molecular Formula C40H76NO8P, Purity >99%, Formula Weight 730.007, Storage Temperature -20°C, 1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine
Avanti Polar Lipids 18:1 PS (DOPS) | 90693-88-2 | MFCD00133436 | 200mg
18:1 PS (DOPS) | Putity: >99% | MW: 810.025 | 90693-88-2 | MFCD00133436 | 200mg
![Medchemexpress LLC 3-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylpropan-1-amine | 1217306-46-1 | >98.0% | C44H81NO2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261464.png-250.jpg)
Medchemexpress LLC 3-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylpropan-1-amine | 1217306-46-1 | >98.0% | C44H81NO2 | 10MG
A synthetic cationic lipid used in the formulation of nucleic acid-lipid particles (LNPs) for research delivery of RNA and DNA. It promotes encapsulation and cellular uptake of nucleic acids when combined with helper lipids and is supplied for laboratory research use only.
- Cationic lipid for formulation of nucleic acid-lipid particles.
- Facilitates encapsulation and delivery of RNA and DNA.
- High purity suitable for research applications.
- Powder form, soluble in DMSO for preparation of stock solutions.
- Recommended storage at -20°C to maintain stability.